Who acts Mrs. Wheeler mother? Which actress takes on the role of Karen Wheeler in the show? Who is the performer behind Karen Wheeler? Karen is brought to life by which actress? Which actor plays the character of Karen the mother on the show? Whom is the talent bringing Karen Wheeler's character to life? What performer takes on the role of Karen Wheeler in the series? Who acts Karen Mrs. Wheeler? Whom is the talented individual embodying Karen Wheeler on the series? What actor incarnates the character of Karen Wheeler to the screen?